Precision Bio therapeutics: The concept of the individualised approach to managing illness and its treatment

Over the time, there has been rapid advancement in bio therapeutic. Bio therapeutic has seen significant improvements particularly due to the enhancement in knowledge of genetic and molecular processes in disease state. It has led to the emergence of precision bio therapeutics which is the approach that uses medical treatment packages that are unique to every individual. Precision biotherapeutics can be considered as significant development in the field of providing individualized approach to various diseases with higher efficiency as compared to conventional treatment.

Essentially, precision biotherapeutics is informed by the genetic make-up, molecular characteristics, and surrounding conditions of clients. This process differs from traditional treatments where treatment modalities are usually developed with reference to standardized responses in populations instead of the anthropology of the disease in the individual. This change is due to the development of genomics, proteomics as well as the fields of bioinformatics that avail information on molecular characteristics of a variety of disorders.

Another factor that has contributed to the beginning of the precision biotherapeutics revolution is the capacity to understand an individual’s genetics like through genomic sequencing. Genetic mutations or variations that result in disease enable the researchers and clinicians to design special treatments that focus on the causes of the diseases in their genetic structure. For instance, precision biotherapeutic in oncology has resulted in generation of targeted therapies for malignant growths that are targeted to genetic changes within these growths. Imatinib for chronic myeloid leukemia and trastuzumab for HER-2 positive breast cancer are prime examples of how targeted therapy is much more effective in comparison to traditional chemotherapy by reducing toxicity, enhanced effectiveness and overall patient care.

Furthermore, precision biotherapeutics do not only go genetic approach but also cover molecular targets such as protein and metabolic characteristics. For instance, application of biomarker in order to pinpoint patients who are likely to benefit from certain treatment increases the effectiveness of biotherapeutic.

However, in view of futuristic precision biotherapeutics several issues persist. This is perhaps the most major challenge given that clinicians and researchers face numerous difficulties in using multiple forms of data including genetics, proteomics, and clinical data towards developing effective therapies. Further, precision therapies entail higher costs of development and implementation to make them more common. It is important that these advancements reach all patients of all financial status for precision medicine to reach its potential.

Another difficulty is in the fact that new discoveries and improved evidence require specialization updates to the treatment concepts. This steady stream of advance knowledge of diseases and illnesses, necessitates a constant evolution of these therapy treatments as continued data floods in. Consequently, precision biotherapeutics can be regarded as one of the most promising breakthroughs in terms of the development of more individualized and efficient methods of treatment. Given that the presented genetic, molecular, and environment therapies are designed ad individual patiem profiles, it is expected to improve efficacy and ameliorate risk avoidance. Current trends are promising and only needs some more development in this particular area, it brings the hope for a future where treatments are customised as the individuals that require them. While advancing in the use of precision bio therapeutics, we are heading to a new era of the precise patient treatment with optimal therapeutic regimes designed for every individual.

Yash Dilip Phalke

University/College name : Indian Institute of Technology , IIT (BHU) , Varanasi