Rapid climate change is a chief factor that lends to yield loss in major food as well as cash crops all over the world. The emergence of adverse environmental conditions has affected almost all aspects of agriculture and even increased the crops’ susceptibility to other elements, especially plant viruses. The adverse effect of climate and its associated factors on agriculture has been worsening through the years. But, the recent Covid-19 pandemic has put the problem into focus as most agriculturists have suffered huge losses, as they were unable to tend to the crops, leaving them unattended and exposed to the vagaries of their environment. Therefore, there is a need to explore both the basic and applied facets of agricultural biotechnology to come up with long- and short-term solutions for developing climate resilient plants. Hence, the current approach has been designed keeping in mind the current and future needs of agriculture.