Extra Mural Projects

The following extra-mural projects are under progress (ongoing) at the Institute of Life Sciences

Name of the ProjectFunding
Agency
Name of Principal
Investigator
Total CostPeriod of the Project
Partnership Programme on Sustainable Bio resources Management DBT-IBSDDr. Ajay Parida8280000.002017 to 2019
International Associated Laboratory in the area of Systems Immunology and Genetics of Infectious Diseases (LIA-SIGID)DBTDr. B. Ravindran3400000.002015 to 2019
Reprogramming deleterious inflammatory Monocytes in Human SepsisDBTDr. B. Ravindran5659600.002015 to 2018
Study to translate CHTX and/or its derivatives for therapeutic intervention in SepsisDBT - BIRACDr. B. Ravimdran2290000.002016 to 2018
Study of spatio-temporal variation in expression of cell cycle regulators in spikelets of rice cultivars contrast for panicle compactness and grain fillingSERBDr. B. P. Shaw3588517.002017 to 2020
Understanding role of DNA polymerase eta dependent trans-lesion DNA synthesis in pathogenicity of Candida albicansDBTDr. N. Acharya7378000.002016 to 2019
Deciphering the role of DNA polymerase delta dependent mutagenesis induced morphogenesis, multidrug resistance and pathogenicity of a pathogen C albicansSERBDr. N. Acharya6272000.002016 to 2019
Molecular Characterization of biofilm produced by coral associated bacteria isolated from Andaman SeaDBTDr. S. K. Das3921216.002014 to 2018
Studies on interactions of plant transcription factors in promoters from plant infecting pararetrovirusesDBTDr. N. Dey4687200.002015 to 2018
Implication of bacteria derived human defensin in burn injury and wound healingSERBDr. N. Dey4430907.002016 to 2019
Studies in in vitro interaction between Arabidopsis Transcription factors TGA and WRKY leading to Salicylic acid mediated gene activation in Cestrum yellow leaf curling virus (CmYLCV) promoters DBT -Tata InnovationDr. N. Dey2700000.002016 to 2019
Studies on interaction of plant transcription factors in Full length transcript-promoter fragment of plant infecting Petunia Vein CleaningVirusSERBDr. N. Dey3697056.002016 to 2019
Global profiling and significance of alternative splicing events regulated by polypyrimidine track binding protein 2 (PTBP 2) in the advanced stages of chronic myeloid leukemiaDBTDr. S. Chakraborty37160000.002015 to 2020
Comparative analysis of acetylation and acetylation deficient mutant form Ecotropic Viral Integration site 1 haematopoietic cellsSERBDr. S. Chakraborty2590000.002015 to 2018
Dissecting co-repressor-centered gene regulatory network underlying dentritic cell immune responses controlling T helper cell differentiation DSTDr. Sunil K. Raghav3669500.002015 to 2018
Integrative genomics approach to identify the role of zinc finger transcription factors ZEB1 & ZEB2 in dendritic cells and its impact on T helper cell differentiationSERBDr. Sunil K. Raghav5732000.002016 to 2019
Integrative genomics approach to identify the role of co-regulators in dendritic cell immune responses and its impact on T helper cell differentiationDBTDr. Sunil K. Raghav5403200.002017 to 2020
Structural characterization of Influenza A virus matrix protein M1 interaction with host nucleosomesDBTDr. Dileep Vasudevan7318038.002014 to 2017
Structural basis of dengue virus capsid protein interaction with the human death domain-associated protein daxxCSIRDr. Dileep Vasudevan1500000.002015 to 2018
Host nucleosomes forming a docking station for Dengue virus capsid protein C- a structural analysisSERBDr. Dileep Vasudevan4703700.002015 to 2018
Design, synthesis and biological evaluation of novel FtsZ inhibitors as potential anti tubercular agents.DBTDr. T.K Beuria4505000.002013 to 2017
Investigating the potential tumor suppressive activity of SARI (Suppressor of AP-1 regulated by interferon) in Oral Squamous Cell CarcinomasDBT - RGCBDr. Rupesh Dash2500000.002015 to 2018
Restoring cell death in chemoresistant oral squomous cell carcinomas (OSCC)SERBDr. Rupesh Dash4604000.002016 to 2019
Tumour Vascular targeting using small molecule inhibitorsDBT - RGCBDr. Rajeeb Swain2500000.002015 to 2018
Understanding the development and function of kidney using zebrafishSERBDr. Rajeeb Swain6669000.002017 to 2020
Functional role of MAGEA3- cancer- testis antigen in pancreatic cancerDBTDr. Shantibhusan Senapati4170000.002017 to 2020
Role of Mitochondrial dynamics in Dengue virus life cycle and disease pathogenesisDBT - Welcome TrustDr. Gulam H Syed29239100.002016 to 2021
Unravelling the molecular mechanism(s) underlying Hepatitis C virus morphogenesis and SecretionSERBDr. Gulam H Syed5209056.002017 to 2020
Understanding the role of IRGM-mediated innate immune responses in diseaseDBT - Welcome TrustDr. Santosh Chauhan35850408.002016 to 2021
Determine the mechanism and therapeutic potential of ZKSCAN3- mediated autophagySERBDr. Santosh Chauhan3697056.002016 to 2019
Malarial Parasite Biology: An avenue to discover new drug targets (Phase-II)DBTDr. Arun V. Nagaraj9091000.002016 to 2021
Development of Specific Inhibitor of Chikungunya VirusSERBDr. Soma Chattopadhyay2150200.002016 to 2019
Identification and characterization of differentially expressed host proteins for both S 27 and DRDE – 06 strains of Chikungunya virus in mouse model : Implications in understanding its epidemic potentialSERBDr. Soma Chattopadhyay3358000.002016 to 2019
Development of 1-[(2-methylbenzimidazol-1-yl) methyl]-2-oxo-indolin-3-ylidene] amino] thiourea ( MBZM-N-IBT) as specific inhibitor of Chikungunya virusDBTDr. Soma Chattopadhyay2489600.002017 to 2020
Study on Persistence of Japanese encephalitis in reservoir host, pig in JE endemic area of Odisha, Manipur and AssamDBT-IBSDDr. Soma Chattopadhyay3714400.002017 to 2019
ATX axis in Satallite Cells and Muscle RepairDBTDr. Vivek Rai4625000.002017 to 2020
Si-RNA conjugated drug loaded mesoporous silica nanoparticles for lung cancer therapySERBDr. Fahima Dilnawaz2360000.002014 to 2017
Nanomedicinal triple therapy with gemcitabine, hedgehog inhibitor and immune-stimulant : A therapeutic boon for pancreatic cancerDSTDr. Chandana Mohanty3223000.002015 to 2018
Proteomic profiling of saliva and oral premalignant lesions by reverse-phase protein array to identify potential diagnostic biomarkersDBTDr. Neera Singh2610000.002015 to 2018
Investigating the role of a novel RING domain E-3-ubiquitin ligase, DZIP3 in regulation of cell cycle and cancer progressionDSTDr. Swati Chauhan3090000.002016 to 2019
Toll like receptor (TLR) Polymorphisms and function: A clinical and experimental study in dengue infectionSERBDr. A. Rajkumar Patro3000000.002015 to 2018
Characterization of novel duodenal ulcer promoting (dupA) protein of Helicobacter pyloriSERBDr. Jawed Alam3420000.002015 to 2018