The following extra-mural projects are under progress (ongoing) at the Institute of Life Sciences
| Name of the Project | Funding Agency | Name of Principal Investigator | Total Cost | Period of the Project |
|---|---|---|---|---|
| Partnership Programme on Sustainable Bio resources Management | DBT-IBSD | Dr. Ajay Parida | 8280000.00 | 2017 to 2019 |
| International Associated Laboratory in the area of Systems Immunology and Genetics of Infectious Diseases (LIA-SIGID) | DBT | Dr. B. Ravindran | 3400000.00 | 2015 to 2019 |
| Reprogramming deleterious inflammatory Monocytes in Human Sepsis | DBT | Dr. B. Ravindran | 5659600.00 | 2015 to 2018 |
| Study to translate CHTX and/or its derivatives for therapeutic intervention in Sepsis | DBT - BIRAC | Dr. B. Ravimdran | 2290000.00 | 2016 to 2018 |
| Study of spatio-temporal variation in expression of cell cycle regulators in spikelets of rice cultivars contrast for panicle compactness and grain filling | SERB | Dr. B. P. Shaw | 3588517.00 | 2017 to 2020 |
| Understanding role of DNA polymerase eta dependent trans-lesion DNA synthesis in pathogenicity of Candida albicans | DBT | Dr. N. Acharya | 7378000.00 | 2016 to 2019 |
| Deciphering the role of DNA polymerase delta dependent mutagenesis induced morphogenesis, multidrug resistance and pathogenicity of a pathogen C albicans | SERB | Dr. N. Acharya | 6272000.00 | 2016 to 2019 |
| Molecular Characterization of biofilm produced by coral associated bacteria isolated from Andaman Sea | DBT | Dr. S. K. Das | 3921216.00 | 2014 to 2018 |
| Studies on interactions of plant transcription factors in promoters from plant infecting pararetroviruses | DBT | Dr. N. Dey | 4687200.00 | 2015 to 2018 |
| Implication of bacteria derived human defensin in burn injury and wound healing | SERB | Dr. N. Dey | 4430907.00 | 2016 to 2019 |
| Studies in in vitro interaction between Arabidopsis Transcription factors TGA and WRKY leading to Salicylic acid mediated gene activation in Cestrum yellow leaf curling virus (CmYLCV) promoters | DBT -Tata Innovation | Dr. N. Dey | 2700000.00 | 2016 to 2019 |
| Studies on interaction of plant transcription factors in Full length transcript-promoter fragment of plant infecting Petunia Vein CleaningVirus | SERB | Dr. N. Dey | 3697056.00 | 2016 to 2019 |
| Global profiling and significance of alternative splicing events regulated by polypyrimidine track binding protein 2 (PTBP 2) in the advanced stages of chronic myeloid leukemia | DBT | Dr. S. Chakraborty | 37160000.00 | 2015 to 2020 |
| Comparative analysis of acetylation and acetylation deficient mutant form Ecotropic Viral Integration site 1 haematopoietic cells | SERB | Dr. S. Chakraborty | 2590000.00 | 2015 to 2018 |
| Dissecting co-repressor-centered gene regulatory network underlying dentritic cell immune responses controlling T helper cell differentiation | DST | Dr. Sunil K. Raghav | 3669500.00 | 2015 to 2018 |
| Integrative genomics approach to identify the role of zinc finger transcription factors ZEB1 & ZEB2 in dendritic cells and its impact on T helper cell differentiation | SERB | Dr. Sunil K. Raghav | 5732000.00 | 2016 to 2019 |
| Integrative genomics approach to identify the role of co-regulators in dendritic cell immune responses and its impact on T helper cell differentiation | DBT | Dr. Sunil K. Raghav | 5403200.00 | 2017 to 2020 |
| Structural characterization of Influenza A virus matrix protein M1 interaction with host nucleosomes | DBT | Dr. Dileep Vasudevan | 7318038.00 | 2014 to 2017 |
| Structural basis of dengue virus capsid protein interaction with the human death domain-associated protein daxx | CSIR | Dr. Dileep Vasudevan | 1500000.00 | 2015 to 2018 |
| Host nucleosomes forming a docking station for Dengue virus capsid protein C- a structural analysis | SERB | Dr. Dileep Vasudevan | 4703700.00 | 2015 to 2018 |
| Design, synthesis and biological evaluation of novel FtsZ inhibitors as potential anti tubercular agents. | DBT | Dr. T.K Beuria | 4505000.00 | 2013 to 2017 |
| Investigating the potential tumor suppressive activity of SARI (Suppressor of AP-1 regulated by interferon) in Oral Squamous Cell Carcinomas | DBT - RGCB | Dr. Rupesh Dash | 2500000.00 | 2015 to 2018 |
| Restoring cell death in chemoresistant oral squomous cell carcinomas (OSCC) | SERB | Dr. Rupesh Dash | 4604000.00 | 2016 to 2019 |
| Tumour Vascular targeting using small molecule inhibitors | DBT - RGCB | Dr. Rajeeb Swain | 2500000.00 | 2015 to 2018 |
| Understanding the development and function of kidney using zebrafish | SERB | Dr. Rajeeb Swain | 6669000.00 | 2017 to 2020 |
| Functional role of MAGEA3- cancer- testis antigen in pancreatic cancer | DBT | Dr. Shantibhusan Senapati | 4170000.00 | 2017 to 2020 |
| Role of Mitochondrial dynamics in Dengue virus life cycle and disease pathogenesis | DBT - Welcome Trust | Dr. Gulam H Syed | 29239100.00 | 2016 to 2021 |
| Unravelling the molecular mechanism(s) underlying Hepatitis C virus morphogenesis and Secretion | SERB | Dr. Gulam H Syed | 5209056.00 | 2017 to 2020 |
| Understanding the role of IRGM-mediated innate immune responses in disease | DBT - Welcome Trust | Dr. Santosh Chauhan | 35850408.00 | 2016 to 2021 |
| Determine the mechanism and therapeutic potential of ZKSCAN3- mediated autophagy | SERB | Dr. Santosh Chauhan | 3697056.00 | 2016 to 2019 |
| Malarial Parasite Biology: An avenue to discover new drug targets (Phase-II) | DBT | Dr. Arun V. Nagaraj | 9091000.00 | 2016 to 2021 |
| Development of Specific Inhibitor of Chikungunya Virus | SERB | Dr. Soma Chattopadhyay | 2150200.00 | 2016 to 2019 |
| Identification and characterization of differentially expressed host proteins for both S 27 and DRDE – 06 strains of Chikungunya virus in mouse model : Implications in understanding its epidemic potential | SERB | Dr. Soma Chattopadhyay | 3358000.00 | 2016 to 2019 |
| Development of 1-[(2-methylbenzimidazol-1-yl) methyl]-2-oxo-indolin-3-ylidene] amino] thiourea ( MBZM-N-IBT) as specific inhibitor of Chikungunya virus | DBT | Dr. Soma Chattopadhyay | 2489600.00 | 2017 to 2020 |
| Study on Persistence of Japanese encephalitis in reservoir host, pig in JE endemic area of Odisha, Manipur and Assam | DBT-IBSD | Dr. Soma Chattopadhyay | 3714400.00 | 2017 to 2019 |
| ATX axis in Satallite Cells and Muscle Repair | DBT | Dr. Vivek Rai | 4625000.00 | 2017 to 2020 |
| Si-RNA conjugated drug loaded mesoporous silica nanoparticles for lung cancer therapy | SERB | Dr. Fahima Dilnawaz | 2360000.00 | 2014 to 2017 |
| Nanomedicinal triple therapy with gemcitabine, hedgehog inhibitor and immune-stimulant : A therapeutic boon for pancreatic cancer | DST | Dr. Chandana Mohanty | 3223000.00 | 2015 to 2018 |
| Proteomic profiling of saliva and oral premalignant lesions by reverse-phase protein array to identify potential diagnostic biomarkers | DBT | Dr. Neera Singh | 2610000.00 | 2015 to 2018 |
| Investigating the role of a novel RING domain E-3-ubiquitin ligase, DZIP3 in regulation of cell cycle and cancer progression | DST | Dr. Swati Chauhan | 3090000.00 | 2016 to 2019 |
| Toll like receptor (TLR) Polymorphisms and function: A clinical and experimental study in dengue infection | SERB | Dr. A. Rajkumar Patro | 3000000.00 | 2015 to 2018 |
| Characterization of novel duodenal ulcer promoting (dupA) protein of Helicobacter pylori | SERB | Dr. Jawed Alam | 3420000.00 | 2015 to 2018 |